• 0487 2304190
  • amalacancerresearch@gmail.com

Dr. K. K. Janardhanan


ramankutty

Dr. K. K. Janardhanan

Professor
Dept. of Microbiology
(+91) - 487-2304190
kkjanardhanan@yahoo.com
kkjanardhanan@acrcs.org

PUBLICATIONS

  • Janardhanan, K.K. and Husain, A 1982. Studies on the isolation, purificationand identification of tenuazonic acid , a phytoxin produced by Alternaria alternata (Fr.) causing leaf blight of Datura innoxia Mill. Mycopathologia 83; 135-140
  • Janardhanan, K.K. Sattar,A and Husain, A 1984 Production of fumigaclavine A by Aspergillus tamarii Kita. Can.J.Microbiology 30: 247-250
  • Antony, M,Gupta, K.P, Janardhanan, K.K. and Mehrotra, N.K. 1991 Inhibition of mouse tumor promotion by tenuazonic acid Cancer Letters 61: 21-26
  • Jose,N and Janardhanan. K.K. 2000 Antioxidant and antitumor activity of Pleurotusflorida. Curr.Sci. 79: 941-943
  • Ajith, T.A. and Janardhanan.K.K. 2002 Antioxidant and antihepatotoxic activities of Phellinus rimosus (Berk) Pilat J.Ethnopharmacology 81: 387-391
  • Antony,M; Shukla, Y. and Janardhanan.K.K. 2002 Protective effect of tenuazonic acid against Dimethylbenz (a) anthracene induced skin carcunogenesis. Tertogen. Carcinoge. Mutagen. 22 : 309-314
  • Lakshmi,B; Ajith,T.A; Sheena,N; Nidhi,G and Janardhanan.K.K 2002 Antiperoxidative, anti-inflammatory and antimutagenic activities of ethanol extract of the mycelium of Ganoderma lucidum occurring in South India. Tratogen.Carcinogen.Mutagen. 22: 85-97
  • Ajith, T.A. and Janardhanan.K.K. 2003 Cytotoxic and antitumor activities of a polypore macro-fungus, Phellinus rimosus (Berk)Pilat. J.Ethnopharmacology 84: 157-16
  • Antony,M; Shukla,Y. and Janardhanan.K.K 2003 Potential risk of acute hepatotoxicity of Kodo poisoning due to exposure to cyclopiazonic acid. J.Ethnopharmacology 87:211-214
  • Lakshmi,B; Ajith,T.A.; Jose,N and Janardhanan.K.K. 2006 Antimutagenic activity of methanolic extractofGanoderma lucidum and its effect on hepatic damage caused by benzo[a]pyrene. J.Ethnopharmacology 107: 297-303
  • Ajith, T. A and Janardhanan, K.K. 2007 Indian medicinal mushrooms as a source of antioxidant and Antitumor agents.. J. Clinical Biochem. Nutrition 40: 157-162
  • Nitha B, Janardhanan KK. 2008 Aqueous-ethanolic extract of morel mushroom mycelium Morchella esculenta, protects cisplatin and gentamicin induced nephrotoxicity in mice. Food Chem Toxicol. 46:3193-9.
  • Sudheesh NP, Ajith TA, Janardhanan KK. 2009 Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged rat. Biogerontol.10:627-36.
  • Ajith TA, Sudheesh NP, Roshny D, Abishek G, Janardhanan KK. 2009 Effect of Ganoderma lucidum on the activities of mitochondrial dehydrogenases and complex I and II of electron transport chain in the brain of aged rats. Exp Gerontol..44:219-23.
  • Sudheesh NP, Ajith TA, Janardhanan KK, Krishnan CV.2009 Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rat. Food Chem Toxicol. 47:2124-8.
  • Sudheesh NP, Ajith TA, Janardhanan KK, Krishnan CV. 2010 Effect of Poly-MVA, a palladium alpha-lipoic acid complex formulation against declined mitochondrial antioxidant status in the myocardium of aged rats. Food Chem Toxicol. 4:1858-62.
  • Sudheesh NP, Ajith TA, Ramnath V,Janardhanan KK. 2010 Therapeutic potential of Ganoderma lucidum (Fr.) P. Karst. against the declined antioxidant status in the mitochondria of post-mitotic tissues of aged mice. Clin Nutr. 29:406-12.
  • Pillai, T.G. Nair, C.K.K. and Janardhanan.K.K. 2010. Enhancement of repair of radiation induced DNA srand break in human cells by Ganoderma lucidum plysccharides. Food Chem. 199: 1040 – 1043
  • Ajith TA and Janardhanan KK. 2011 Antimutagenic effect of Phellinus rimosus (Berk) Pilat against chemical induced mutations of histidine dependent Salmonella typhimurium strains Food Chem Toxicol, 49: 2676-268
  • Sudheesh NP, Ajith TA, Janardhanan KK, Krishnan CV. 2011 Palladium-α-lipoic acid complex attenuates alloxan-induced hyperglycemia and enhances the declined blood antioxidant status in diabetic rat. J Diabetes. 3:293-300
  • Smina TP, De S, Devasagayam TP, Adhikari S, Janardhanan KK 2011Ganoderma lucidum total triterpenes prevent radiation-induced DNA damage and apoptosis in splenic lymphocytes in vitro. Mutat Res. 726:188-94.
  • Sudheesh NP, Ajith TA, Janardhanan KK. 2012 Ganoderma lucidum protects liver mitochondrial oxidative stress and improves the activity of electron transport chain in carbon tetrachloride intoxicated rats. Hepatology Res. 42:181-91
  • Joseph, J, Sudeesh.N.P., Janardhanan KK. 2012 Protective effect of polysaccharide-protein complex from a polypore mushroom, Phellinus rimosus against radiation-induced oxidative stress. Redox Rep. 17:22-7
  • Sudheesh, N.P. ,Ajith, T.A., Mathew, J, Nima, N, and Janardhanan. K.K. 2012. Ganodrma lucidum protests liver mitochondrial oxidative stress and improve s the activity of electron transport chain in carbontetrachloride intoxicated rats. Hepatol.Res. 42: 181-191.
  • Sudheesh NP, Ajith TA, Janardhanan KK. 2013 Ganoderma lucidum ameliorate mitochondrial damage in isoproterenol-induced myocardial infarction in rats by enhancing the activities of TCA cycle enzymes and respiratory chain complexes. Int J Cardiol.165: 117-125
  • Sudheesh NP, Ajith TA, Janardhanan KK. 2013 Hepatoprotective effects of DL-α-Lipoic acid and α-Tocopherol through amelioration of the mitochondrial oxidative stress in acetaminophen challenged rats. Toxicol Mech Methods.23:368-76.
  • Joseph, S, Janardhanan,K.K., George, V, Baby, S. 2014 A new eopxidic ganoderic acid and other phytoconstituents isolated from Ganoderma lucidum . Phytochem. Letters, 61: 335-342
  • Smina, T.P., Maurya, D.K., Devasagayam,T.P.A., and Janardhanan, K.K. 2015 Protection of radiatin induced DNA and membrane damages by total tritepenes isolated from Ganoderma lucidum (Fr.) P.Karst. Chemico.Biol. Intera. 233: 1-7
  • .Veena, R.K., Ajith, T.A., Janardhanan, K.K., 2018 Lingzhi or Reishi medicinal mushroom, (Agaricomycetes) prevents Doxorubicin –induced cardiotoxicity in rats. Int.J.Med.Mushrooms.20 : 761-774
  • Veena , R.K., Joy Carmel, E., Ramya, H., Ajith, T.A., Wasser, S.P., Janardhanan,K.K. 2020 . Caterpillar medicinal mushroom, Cordyceps militaris (Ascomycetes) mycelia attenuates Doxorubicin –induced oxidative stress and upregulates Kerbs cycle dehydrogeneasees activity and ATP level in rat brain. Int.J.Med.Mushrooms. 22:593-604.