• 0487 2304190
  • amalacancerresearch@gmail.com

Dr. Jose Jacob, MD


ramankutty

Dr. Jose Jacob, MD

Professor, Dept. of Biochemistry
Amala Cancer Research Centre,
(+91) - 487-2304190
josejacob.amala@gmail.com
josejacob.amala@acrcs.org

Postdoctoral Research: Research Associate; Jan.1985 to Dec. 1991; (Subjects familiarized)

  • 3 years at Indian Institute of Science, Bangalore (Cell Biology, Spectroscopy)
  • 3 years at Sree Chitra Tirunal Inst. of Sci. & Tech., Thiruvananthapuram (Cell Biology,Microscopy)
  • 1 year at Center for Cellular and Molecular Biology, Hyderabad (Molecular Biology)
  • Specific Research Experience (Completed work, only few are published)
    1 Department of Biochemistry, Amala Institute of Medical Sciences, Thrissur.
     
  • Development of a fluorescent probe for Alkaline phosphatase in bile
  •  
  • A method for separation of cellular organelles using aggregation method
  •  
  • Risk assessment and baseline reference interval calculation of insulin in Type 2 Diabetes Mellitus
  •  
  • Evaluation of the disease state and control of blood sugar in uncontrolled Type 2 Diabetes Mellitus
  •  
  • Reference interval of Erythropoietin and the correlates of Erythropoietin in healthy individuals and in disease
  •  
  • Baseline reference interval calculation of bone markers and variation of urine NTX levels in collagen related diseases
  •  
  • Development of methods for fluorescence data analysis, evaluation of preanalytical sample influences, quality control, sequence data analysis for RT-PCR of Hepatitis C Virus for improving sensitivity of detection
  • 2 Dept. of Biochemistry, KMC, Manipal
     
  • Development of different environmental sensitive fluorescent probes for calcium stores and pH in Endoplasmic reticulum and Golgi Apparatus
  •  
  • Influence of benzyl benzoate on cellular calcium stores
  •  
  • Hydrogen peroxide of urine in oxidative stress conditions
  • 3 Molecular Biophysics Unit, Indian Institute of Sciences, Bangalore
     
  • Influence of chemotactic receptors, their agonists and antagonists on neutrophils
  •  
  • Development of Chlortetracycline as a probe for intracellular calcium stores
  • 4 Centre for Cellular and Molecular Biology, Hyderabad
     
  • Restriction Fragment Length Polymorphism and DNA fingerprinting
  • 5 SCTIMST, Trivandrum
     
  • Influence of Lanthanides on cultured human fibroblasts
  • 6 Department of Biochemistry, All India Institute of Medical Sciences, New Delhi
     
  • Immune complexes and antibodyto Mycobacterium leprae and related Mycobacteria in leprosy patients.
  • Present Ongoing Research Programs

    • Risk assessment and baseline reference interval calculation of insulin and C peptide in Type 2 Diabetes Mellitus
    • Evaluation of the disease state and control of blood sugar in uncontrolled Type 2 Diabetes Mellitus
    • Reference interval of Erythropoietin and the correlates of Erythropoietin in healthy individuals and in disease
    • Baseline reference interval calculation of bone markers and variation of urine NTX levels in collagen related diseases
    • Development of methods for fluorescence data analysis, evaluation of preanalytical sample influences, quality control, sequence data analysis for RT-PCR of Hepatitis C Virus for improving sensitivity of detection
    • Clinical interpretations of serum lipid profile and its correlates

    Present Ongoing Research Programs

    • Ph.D. candidates guided: Completed: 6; (Indirectly Guided Dissertation: 1; Ongoing: 3;)
    • MD Dissertation: 4
    • M.Phil. candidates guided: 2
    • M. Sc. Dissertations guided: more than 100
    • DNB dissertations guided: 1