• 0487 2304190
  • amalacancerresearch@gmail.com

Publications


Recent Publications

  1. Illam S P, Hussain A, Elizabeth A, Narayanankutty A, Raghavamenon A C (2019) Natural combination of phenolic glycosides from fruits resists pro-oxidant insults to colon cells and enhances intrinsic anti-oxidant status in mice. Toxicology Reports 6, 703-711.
  2. Cyril N, George J B, Joseph L, Raghavamenon A C, Silas V P (2019) Assessment antioxidant, antibacterial and antiproliferative (lung cancer cell line A 549) activities of green synthesized nanoparticles from Derris trifoliate. Toxicology Research 8(2), 297-308.
  3. D L Sheela, A Narayanankutty, P A Nazeem, A C Raghavamenon (2019) Lauric acid induce cell death in colon cancer cells mediated by the epidermal growth factor receptor down regulation: An Insilco and invitro study. Human & Experimental Toxicology DOI: 096032.
  4. Smitha K. Ramavarma, Ansa P. Unnikrishnan, Babu. T. Devassy and Achuthan C. Raghavamenon (2019) In vitro cytotoxic and antiproliferative activities of Uvarianarum seed oil (UNSO) Int. J. Adv. Res. 6(9), 912-916
  5. Shaji E. Mathew, Smitha K. Ramavarma, ThekkekaraDevassyBabu, Balu T. Kuzhivelil and Achuthan C. Raghavamenon (2019) Preliminary assessment on phytochemical composition cytotoxic and antitumor efficacy of Simaroubaglauca DC. Leaf methanolic extract.Annals of Phytomedicine8(2): 121-126, 2019
  6. Meera N and Babu T D (2019) Evaluation of anti-tumour potential of Cynometratravancorica bed. International Journal of Scientific Research 8(6) 61-63.
  7. Markose B, Rajesh B and Babu T D (2019) Acute and sub-acute toxicity evaluation of calcium carbide and ethylene glycol in Wistar albino rats. Journal of Basic and clinical Physiology and Pharmacology 29;31(1)
  8. Kuttan R, Kuttan G (2019) Aqueous extract of ViscumangulatumHeyne ex DC inhibits lung metastasis induced by B16F10 melanoma cells in C57BL/6 mice. Annals of PhytomedicineDOI: 10.21276/ap.2019.8.1.11.
  9. Kuttan G, Kuttan R (2019)Immunopotentiating activity of hemiparasitic plants of familyViscaceaewith special referencetoViscumangulatumHeyne ex DC. Annals of PhytomedicineDOI: 10.21276/ap.2019.8.1.13.
  10. Purushothaman B P, Kuttan R (2019) Effect of green tea extract on the carbofuran induced toxicity in wistar rats. Annals of PhytomedicineDOI: 10.21276/ap.2019.8.2.6.
  11. Shepherd, Mickle A D, Copits B A, Karlsson P, Kadunganattil S (2018) Macrophage-to-sensory neuron crosstalk mediated by Angiotensin II type-2 receptor elicits neuropathic pain. Journal of Neuroscience 38 (32), 7032-7057.
  12. Shepherd AJ, Mickle AD, Kadunganattil S, Hu H, Mohapatra DP (2018) Parathyroid Hormone-Related Peptide Elicits Peripheral TRPV1-dependent Mechanical hypersensitivity. Frontiers in cellular Neuroscience 12:38. doi: 10.3389/fncel.2018.00038.
  13. Narayanankutty A, Anil A, Illam S P, Kandiyil S P, Raghavamenon A C (2018) Non-polar lipid carbonyls of thermally oxidised coconut oil induces hepatotoxicity mediated by redox imbalance. Prostaglandin Leukotrienes and Essential Fatty acids 138, 45-51.
  14. Chubicka T, Girija D, Deepa K, Salini S, Meera N, Raghavamenon A C, Divya M K and Babu T D(2018) A parasporin from Bacillus thuringiensisnative to Peninsular India induces apoptosis in cancer cells through intrinsic pathway. Journal of Bioscience 43, 407-416.
  15. Nesheera K. K, Sindhu P. C, and Jose Jacob (2018) Exclusion of Deficiencies in Vitamin D, Hemoglobin and Iron in otherwise Healthy Young Adults brings out the Gender Differences in the relationship of Parathyroid Hormone. International J. Sci. Res. 2018, 7, 76-80.
  16. Chubicka T, Girija D, Deepa K, Salini S, Meera N, Raghavamenon C Achuthan, Divya M K and ThekkekaraDevassyBabu (2018) A parasporin from Bacillus thuringiensis native to Peninsular India induces apoptosis in cancer cells through intrinsic pathway. Journal of Biosciences 43, 407-416.
  17. Kallivalappil George GilcyKuttanGirija (2018) Efficacy of punarnavine in restraining organ‑specific tumour progression in 4T1‑induced murine breast tumour model. Inflammopharmacology.
  18. Veena R K, Ajith T A, Janardhanan K K (2018) Lingzhi or Rishi medicinal mushroom, Ganodermalucidum (Agaricomycetes) Preventing donorudicium – induced cardiotxicity in rats. International Journal of Medicinal Mushrooms 20, 761-774.
  19. Ravikumar K S, Clinda Paul C, MeeraPandey, K KJanardhanan (2018)Antioxidant, Antiinflammatory and Antitumour activities of aqueous ethanolic extract of the golden oyster mushroom pleurotuscitrinopioeatus (FR). International Journal of development Research 8, 23507-23512.
  20. HaridasRamya, Ravindran K Veena, K KJanardhanan (2018)Antitumour activity of expolysaccharides produced by an isolate of Ganodermalucidum occurring in South India. International Journal of Pharmacy and Biological Sciences 8, 20-24
  21. ChakrappillyRadhakrishnaMeera, Kainoor K Janardhanan, DevarajanKarunagaran (2018) Antiproliferative and Apoptotic activities of the medicinal mushrooms Phellinusrimosus (Agaricomycetes) on HCT 116 Human Colorectal Carcinoma Cells. International Journal of Medicinal Mushrooms 20,935-945.
  22. KorattuvalappilSankaranarayananRavikumar, HaridasRamya, ThekkuttaparambilAnanthanarayananAjith, Kainoor K Janardhanan, Manzoor Ahmad Sha, Zafar A Reshi and KhurshidIqbalAndvabi (2018) Antioxidant and Anti-inflammatory activities of Bioactive extracts of a polypore mushroom fomitopsispinicola (SW:FR) P.Karst from Kashmir.International Journal of Advanced Research 6, 1144-1156.
  23. GreeshmaPanavalappil, Feba Jose, FathimathuZuharaKarattuthodi and K KJanardhanan (2018) Hypsizygusulmarius (Bull Fr)elm Oyster Mushroom attenuates carbon tetrachloride – induced hepatic injury in Wistar. Indian Journal of Experimental Biology (Accepted)
  24. Binitha P P, Gayathri V and Kuttan R (2018) Oxycartenoid Lutein reverses the toxicity induced by carbofuran in Wistar rats. International Journal of Pharmacy and Pharmaceutical sciences 10, 10-15.
  25. A Narayanankutty, SP Illam, Raghavamenon C Achuthan (2018) Health impacts of different edible oils prepared from coconut (Cocosnucifera): A comprehensive review. Trends in Food Science & Technology 80, 1-7.
  26. A Narayanankutty, Midhun K Gopinath, MuneeraVakayil, Smitha K Ramavarma, ThekkekaraDevassyBabu and Raghavamenon C Achuthan (2018) Non-enzymatic conversion of primary oxidation products of Docosahexaenoic acid into less toxic acid molecules. SpectrochimicaActa Part A: Molecular and Biomolecular Spectroscopy 203, 222-228.
  27. Indu MS, Padikkala J, Raghavamenon C Achuthan (2018) Partially Purified Aqueous Fraction of Desmodium gyrans DC Improves Reverse Cholesterol Transport and Lipoprotein Metabolism in Wistar Rats Fed with High Fat Diet. Journal of Environmental Pathology, Toxicology and Oncology 37(1), 27-41.
  28. Narayanankutty A, Palliyil DM, Kuruvilla K and Raghavamenon C Achuthan (2018) Virgin coconut oil reverses hepatic steatosis by restoring redox homeostasis and lipid metabolism in male Wistar rats. Journal of the Science of Food and Agriculture 98(5), 1757-1764.
  29. M. S. Indu, Jose Padikkala and Raghavamenon C Achuthan (2018) Safety assessment of partially purified HDL enhancing phytocomponents from Desmodiumgyrans dc. International Journal of Advanced Research (IJAR) DOI: 10.21474/IJAR01/6430.6(2),210-217.
  30. Divya M K, Meera N, Raghavamenon AC and Babu T D(2017). Anti-inflammatory and gastro-protective effects of Apodytesdimidiata. South African Journal of Botany 108, 223-228.
  31. Shahid AP, Sasidharan N, Salini S, Padikkala J, Meera N, Raghavamenon AC, Babu TD (2017)Kingiodendronpinnatum, a pharmacologically effective alternative for Saracaasoca in an Ayurvedic preparation, Asokarishta. J Tradit Complement Med 8(1), 244-50.
  32. Veena R K and Janardhanan K K (2017) Ganodermalucidum (FR) P. Karst ameliorate mitochondrial dysfunction inn doxorubicin-induced cardiotoxicity in rats. International Journal of Advanced Research 5(10), 1742-1748.
  33. Menon S, Lawrence L, Vipin P S and Padikkala J (2017) Dasamula plant, Oroxylumindicum root bark extract prevents doxorubicin induced cardiac damage by restoring redox balance. Journal of Ayurveda and Integrative Medicine
  34. RamadasanKuttan; Shivamurthy GR and GirijaKuttan(2017) Potential antitumour and anti-inflammatory activity of six Mistletoe plants in the family Viscaceae present in Western Ghats, International Journal of Pharmacy and Pharmaceutical Sciences, Vol.9, Issue 11
  35. Vijayasteltar L, Jismy I J, Joseph A, Maliakel B, Kuttan R and Krishnakumar I M (2017) Beyond the flavor: A green formulation of Ferula asafetida oleo-gum-resin with fenugreek dietary fibre and its gut health potential. Toxicology Reports 4, 382-390.
  36. Binitha P P and Kuttan R (2017) Protective effect of curcumin against carbofuran induced toxicity in Wistar rats. Journal of Environmental Pathology, Toxicology and Oncology 36(1), 73-86.
  37. Kuttan R and Binitha P P (2017) Neuroprotective effect of curcumin and Emblicaofficinalis on carbofuran induced toxicity in Wistar rats. Book Chapter: Neuroprotective effects of Neurological disorders (John Wiley & Sons Ltd). Editors : TahiraFarooqui and AkhlaqA.Farooqui, Chapter 23, pg.447-461
  38. Kuttan R and Liju V B (2017) Safety evaluation of essential oils. Book chapter 12. Essential Oils in Food Processing: Chemistry, Safety and Applications (IFT series), published by Wiley. Pg. No.339- 359
  39. Nesheera K K, Sindu P C and Jacob J (2017) Clinical evaluation of gender differences in the relationships of erythropoietin with haemoglobin, iron and ferritin in presence and absence of anemia in healthy young adults. International Journal of Cotemporary Medical Research: I Dr. Devanand Gupta (Ed) September 2017, ISSN (Online), 2393-915X.
  40. Francis S, Sindu P C, Nesheera K K and Jacob J (2017) Fasting insulin is better partitioned according to family history of type 2 diabetes mellitus than post glucose load insulin of oral glucose tolerance test in young adults. Journal of clinical and diagnostic research: 1-4 Dr.Hemant Jain (Ed) for JCDR Research and Publications (P) Limited. DOI; 10.7860/ JCDR/2017/27684.9910.
  41. Francis S, Sindu P C, Nesheera K K and Jacob J (2017) Fasting C peptide correlated with fasting insulin and post glucose load C peptides in young adults but the C peptides could not be partitioned into groups with and without family history of type 2 dibetes mellitus. International Journal of Cotemporary Medical Research 4, 467 - 472 Dr. Devanand Gupta (Ed), March. ISSN (Online), 2393-915X.
  42. Narayanankutty A, Jeksy J M, Suseela I M, Smitha K R, Shaji E M, Illam S P, Babu T D, Balu T K and Raghavamenon A C (2017) Deep fried edible oils disturbs hepatic redox equilibrium and heightens lipotoxicity and hepatosteatosis in rats. Human and Experimental Toxicology 36 (9), 919-930. DOI: 10.1177/0960327116674530.
  43. Illam S P, NarayanankuttyA,Shaji E M,Rosemol M J and Raghavamenon A C(2017) Epithelial esenchymal transition in cancer Progression: Preventive Phytochemicals. Recent Patents on Anti-Caicer Drug Discovery, DOI 10.2174/15 74892812666170424150407.
  44. Illam S P, Narayanankutty A and Raghavamenon A C(2017) Polyphenols of Virgin coconut oil prevent pro-oxidant mediated cell death. Toxicology Mechanism and Methods 27(6): 442-450; DOI; 10.1080/15376516.2017.1320458.
  45. Narayanankutty A, Devika M P, KeiaKuruvilla and Raghavamenon A C (2017) Virgin coconut oil reverses hepatic steatosis by restoring redox homeostasis and lipid metabolism in male Wistar rats. Journal of Science of Food and Agriculture, DOI; 10.1002/jsfa.8650.
  46. Shahid A P, Sasidharan N, Salini S, Padikkala J, Nair Meera, Raghavamenon AC and Babu T D (2017) Kingiodendronpinnatum, a pharmacologically effective alternative for Saracaasoca in an Ayurvedic preparation, Asokarishta. Journal of Traditional and Complementary Medicine 8(1): 244–250;DOI: 10.1016/j.jtcme.2017.06.005
  47. Roy N, Nazeem P A, Babu T D, Abida P S, Narayanankutty A, Valsalan R, Valsala P A (2017) EGFR gene regulation in colorectal cancer cells by garlic phytocompounds with special emphasis on S-Allyl-L-cysteine sulfoxide.Interdisciplinary Sciences-Computational. Life Sciences 27, 017-0227, D01; 10.1007/s12539-017-0227-6.
  48. Sheela D L, Nazeem P A, Narayanankutty A, Muthangaparambil S R, Davis S P, James P, Valsalan R, Babu T D and Raghavamenon A C (2017) Coconut phytocompounds inhibits polyol pathway enzymes: Implication in prevention of microvascular diabetic complications prostaglandins, leukotrienes and essential fatty acids (PLEFA), 127, 20-24. DOI;10.1016/j.plefa.2017.1010.1004.
  49. Kumara M, Shylaja M R, Nazeem P A, Babu T D (2017) 6-Gingerol is the most potent anticancerous compound in Ginger (ZingiberofficinaleRosc. Journal of Developing Drugs 6, 1-7. OMICS International, DOI;10.4172/2329- 6631.1000167.
  50. Saewu A, Kadunganattil S, Ragupathy R, Kongmanas K, Astudillo P D, Hermo L, Tanphaichitr N(2017) Clusterin in the mouse epididymis: Possible roles in sperm maturation and capacitation. Reproduction. DOI;10.1530/REP-17-0518 (accepted).
  51. Divya M K, Meera N, Raghavamenon C Achuthan and ThekkekaraDevassyBabu (2017) Anti-inflammatory and gastro-protective effects of Apodytesdimidiata. South African Journal of Botany 108, 223-228.
  52. Kallivalappil George GilcyKuttanGirija (2017) Evaluation of the anti‑inflammatory and urotoxicity ameliorative effects of γ‑humulene containing active fraction of Emilia sonchifolia(L.) DC. Inflammopharmacology.
  53. Narayanankutty A, Anagha K, Shaji E M, Illam S P, Suseela I M, and RaghavamenonA C(2016) Vitamin E, supplementation modulates the effect of Omega 3 fatty acidstreatment in aged rats. Toxicology Mechanism and Methods 27(3), 207-214. DOI:101080/15376516.2016.1273431.
  54. Smina T P, Joseph J, Janardhanan K K (2016) Ganodermalucidum total terpenes prevent y-radiationInduced oxidative stress in Swiss albino mice. Redox Report 21(6) 254-61.
  55. Smina T P, Mathew J, Janardhanan K K (2016) Ganodermalucidum total triterpenes attenuate DLA induced ascites and EAC induced solid tumours in Swiss albino mice. Cellular and Molecular Biology 62(5) 55-59.
  56. Greeshma P V, Zuhara K F, Janardhanan K K (2016) Antioxidant, anti-inflammatory and antitumour activities of cultured mycelia and fruiting bodies of the elmoyster mushroom, Hypsizygusulmarius (Agaricomycetes). International Journal of Medicinal Mushrooms 18(3), 233-244.
  57. Ravikumar K S, Greeshma P V, Georke V and Janardhanan K K (2016) Antioxidant and anti-inflammatory activities of Fomitopsisdochmius (Berk. & Broome) Ryvarden. International Journal of Pharmaceutical Sciences and Research 7 (9), 3666-3674.
  58. Sindhu E R, Nithya T R, Binitha P P and Kuttan R (2016) Amelioration of doxorubicin-induced cardiac and renal toxicity by oxycarotenoid lutein and its Mechanism of action. Journal of Environmental Pathology, Toxicology and Oncology 35(3), 237-247.
  59. Firdous A P, Binitha P P, Kuttan G, Kuttan R (2016) Antitumour activity of meso-zeaxanthine and its mechanism of action. International Journal of Pharmacy and Pharmaceutical Sciences 8 (5), 53-57.
  60. Liju V, Nair G G, Maliakel B, Kuttan R. Krishnakumar I M (2016) Safety Assessment of a standardized polyphenolic extract of clove buds: Subchronic toxicity and mutagenicity studies. Toxicology Reports 3, 439-449.
  61. Roy N, Davis S, Narayanankutty A, Nazeem P A, Babu T D, Abida P S, Valsala PA and Raghavamenon A C (2016) Garlic phytocompounds possess anticancer activity by specifically targeting breast cancer biomarkers: An In silico study. Asian Pacific Journal of Cancer Prevention 17(6), 2883-2888.
  62. Kumar D, Jacob D, Subash P S, Maliakkal A, Johannah NM, Maliakel B, Konda V, Kuttan R, Krishnakumar I M (2016) Enhanced bioavailability and relative distribution offree (unconjugated) curcuminoids following the oral administration of a food-grade formulation with Fenugreek dietary fibre: A randomized double-blind crossover study. Journal of functional Foods 22, 578-587.
  63. Lawrence L, Menon S, Divya M K, Sivaram V P, Padikkala J (2016) Inhibition of Dimethylbenz(a)anthracene (DMBA) croton oil-induced mouse skin tumorigenesis by Gmelinaarborea with potential anti-inflammatory activity. Journal of Environmental Pathology 35(3), 263-272.
  64. Lawrence L, Menon S, Vincent S, Vipin P S, Padikkala J (2016) Radical scavenging and gastroprotective activity of methanolic extract of Gmelinaarborea stem bark. Journal of Ayurveda and Integrative Medicine 7, 78-82.
  65. Lawrence L, Menon S, Vipin P S, Padikkala J (2016) In vitro and in vivo antioxidant potential of Gmelinaarborea stem bark. Journal of Chemical and Pharmaceutical Research
  66. Narayanankutty A, Muneera V, Jeksy J M, Smitha K R, Indu M S, Babu T D and Raghavamenon AC (2016) Omega 3 fatty acids: Do they raise health concern? J S M Biochemistry and Molecular biology 3(1): 1016.
  67. Narayanankutty A, Jeksy J M, Indu M S, Smitha KR, Shaji EM, Soorya P, Babu T D, Balu T K and Raghavamenon A C (2016) Deep fried edible oils disturb hepatic redox equilibrium and heighten lipotoxicity and hepatosteatosis in rats. Human and Experimental Toxicology 36 (9). 919-930. SAGE Journals,10.1177/096 0327116674530.
  68. Lekshmi DS, Nazeem PA, Narayanankutty A. Jeksy JM and Raghavamenon A C (2016) Insilico and wet lab studies reveal the cholesterol lowering efficacy of lauric acid a medium chain fat of coconut oil Plant Foods for Human Nutrition 71(4):410-415.
  69. Murali V and Kuttan G (2016) Antioxidant activity of Curculigoside, a phenolic glucoside from CurculigoorchioidesGaertn. International Journal of Pharmaceutical Research (Accepted for Publn.)
  70. Binitha P P and Kuttan R (2016) Scientific validation on the use of Ayurvedic drugs in cancer therapy. Treatise 21-28.
  71. Gupte R P, Kadunganattil S et al (2016) Convergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylatecyclase-activating polypeptide. Neuro-pharmacology 101, 291-308.
  72. Veena R K, Ajith T A, Janardhanan K KAntonawich F (2016) Anti-tumour effect of palladium 2-lipoic acid complex formulation as an adjunct in radiotherapy. Journal of Environmental Pathology and Oncology 35, 333-342.
  73. B BKuriakose, N AAleyKutty, R Kuttan (2014) Isolation of venom neutralizing fraction from arial parts of Hidyotiscorymbosa. International Journal of Pharmacognosy and Phytochemical Research 6, 271-275.